Radiation Oncology

Mastectomy

Types of Surgery: Mastectomy About Mastectomy This "Helpful Facts" sheet is designed to give you basic information on mastectomy. More detailed information can be provided by your doctor or nurse. If, you have questions or would like additional information, please talk to your doctor or nurse. What is a mastectomy? A mastectomy is the surgical removal of breast
Long-Term Results of a Randomized Trial Comparing Breast-Conserving Therapy With Mastectomy: European Organization for Research and Treatment of Cancer 10801 Trial Reviewers: Li Liu, MD Source: Journal of the National Cancer Institute, Volume 92(14):1143-1150, (July) 2000Précis: Survival is similar after mastectomy, breast-conserving therapy for stage II tumorsIntroductionIt has been well established that either radical mastectomy or breast-conserving therapy results in the same long-term survival
Second Malignancies after Treatment of Early-Stage Breast Cancer: Lumpectomy and Radiation Therapy Versus Mastectomy Reviewers: Li Liu, M.D Source: Journal of Clinical Oncology, Volume 18 (12), 2406-2412 (June) 2000Précis: Radiation for breast cancer is not associated with greater risk of second malignancy.IntroductionAlmost all types of cancer can be caused by exposure to ionizing radiation with exception of chronic lymphocytic leukemia. Recent studies
Long-term Satisfaction and Psychological and Social Function Following Bilateral Prophylactic Mastectomy Reviewers: Li Liu, MD Source: JAMA Volume 284(3): 319-324, (July) 2000Précis: High satisfaction following prophylactic bilateral mastectomyIntroductionThe improved availability to identify women at high risk for breast cancer, such as through genetic testing for BRCA1 and BRCA2 mutation, has intensified the need to define the benefits and
Prognostic Value of p53 for Local Failure in Mastectomy-Treated Breast Cancer Patients Reviewers: Li Liu, MD Source: Journal of Clinical Oncology, Vol. 18, No 9, 1906-1913, (May) 2000IntroductionRandomized clinical trials have established that radiation therapy improves the local regional control and survival in selected breast cancer patients treated with mastectomy. However, only about 50% of patients will benefit from
Twenty-Year Follow-up of a Randomized Trial Comparing Total Mastectomy, Lumpectomy, and Lumpectomy Plus Irradiation for the Treatment of Invasive Breast Cancer Authors: Bernard Fisher, M.D., Stewart Anderson, Ph.D., John Bryant, Ph.D., et al. Source: N Engl J Med 2002, 347:1233-1241 Background The National Surgical Adjuvant Breast and Bowel Project (NSABP) protocol B-04 showed that over 25 years of follow-up there was no significant difference in survival between women treated with a radical
Efficacy of Bilateral Prophylactic Mastectomy in Women with a Family History of Breast Cancer Reviewers: Kenneth Blank, MD Source: The New England Journal of Medicine, January 14, 1999, Volume 340, Number 2BackgroundThe treatment of breast cancer has changed dramatically over the past two decades. Advances have included the recognition that breast conserving surgery when combined with radiotherapy offers similar survival compared to
Effect of Nancy Reagan's Mastectomy on Choice of Surgery for Breast Cancer by US Women Reviewers: John Han-Chih Chang, MD and Kenneth Blank, MD Source: Journal of the American Medical Association 1998; Volume 279: pages 762 - 766.BackgroundCancer treatment can take on various forms. It can include surgery, radiation therapy or chemotherapy. Recommendations on what is required to treat the certain cancer is influenced by extent of
Lumpectomy vs. Mastectomy My mother who is 61 years old has a T1 (bordering on T2) breast cancer diagnosis which qualifies to be treated with a lumpectomy and radiation. What are the reasons for selecting a lumpectomy over a mastectomy? Carolyn Vachani, MSN, RN, AOCN OncoLink's Nurse Educator responds: Researchers began looking at this question in the
Prophylactic Mastectomy Dear OncoLink "Ask the Experts," I do not as yet, have breast cancer, however, I have so many signs and symptoms I am looking for information to help me decide if I should have a mastectomy before cancer develops. Please Help!!! I can't find much at all to aid me in this decision. Ken Blank, MD, and John Han-Chih
Drive Through Mastectomy I've heard that insurance companies are trying to rush inpatient care. Is that going to happen to me? Maggie Hampshire, RN, BSN, OCN of the Abramson Cancer Center of the University of Pennsylvania, responds: Over the last ten years, public anger has been evoked over the move toward outpatient care after breast
Skin Sparing Mastectomy Dear OncoLink "Ask The Experts," What is your opinion of skin sparing mastectomy? Is there any sensation left?Don LaRossa, MD, Professor of Surgery at the University of Pennsylvania Medical School, responds:Skin sparing mastectomy is excellent for many patients who are suitable candidates. Your surgeon can review the options with you to determine
Abdominal Exercise after Mastectomy Dear OncoLink "Ask The Experts," I was diagnosed with breast cancer about 4.5 years ago, and had a mastectomy and TRAM flap reconstruction. Since that time, I have had to wear a support on my abdomen. I originally gained weight, but have lost some of it. I started an intense exercise program about 6 months ago, and now my abdomen is much more
Radiation after Mastectomy with Reconstruction Dear OncoLink "Ask The Experts," I had a left-sided mastectomy with immediate reconstruction and tissue expander. I had DCIS with invasion and had a sentinel lymph node biopsy, which came back with 2 positive nodes out of 11. I'm undergoing chemo with A/C and Taxol for a total of 8 treatments, and my oncologist recommended radiation when I'm
Tamoxifen after Mastectomy Dear OncoLink "Ask The Experts," I had a mastectomy at age 36. The pathology report indicated the presence of both DCIS and LCIS. No lymph node involvement was seen and the estrogen receptor status was negative, so I had no further treatment. Recently, at age 49, I was diagnosed with invasive ductal cancer of my other remaining breast and had a
Mammogram after Mastectomy? Dear OncoLink "Ask The Experts," I had a nipple-sparing mastectomy last year. Do I need to have mammograms because of the nipple sparing? I have seen reference to this in clinical practice guidelines, but I think they mean if you only had one breast removed. Kevin R. Fox, MD, Assistant Director, Clinical Affairs and Associate Professor of
Testing Pre-Mastectomy Dear OncoLink "Ask The Experts," I will have a double mastectomy next week. Someone told me I should get a bone density test and a range of motion (for arms) test. Is that correct? Kathryn Schmitz, PhD, MPH, cancer rehabilitation researcher at the Abramson Cancer Center of the University of Pennsylvania, responds: I would very much agree
Extracapsular Axillary Nodal Extension (ECE) in Breast Cancer: Patterns of Recurrence, Arm Edema, and Survival after Mastectomy with and Without Irradiation Presenter: Robert Kuske, MD Affiliation: Ochsner Clinic/Tulane University School of Medicine, New Orleans, LA Background:The prognostic implications of extracapsular extension (ECE) in breast cancer with axillary lymph node (ALN) disease is debatable. It has not been conclusively demonstrated that having ECE in positive ALNs is an indication
Second Malignancies after Treatment of Early Stage Breast Cancer with Lumpectomy and Radiation or Mastectomy without Radiation Presenter: E. Obedian Affiliation: Yale University School of Medicine Summary:Multiple studies have demonstrated the clinical efficacy of breast conserving therapy (BCT) for early stage breast cancer. Despite decades of experience, however, there are limited data regarding the safety of this treatment, specificially the risk of second
Prophylactic Mastectomy Satisfactory to Majority of Patients A recent study has found that the majority of women at increased risk for breast cancer who elected prophylactic mastectomy as a preventive measure were satisfied with the procedure. Marlene Frost, RN, PhD, and colleagues found that of women who were mailed questionnaires following the procedure, 38 percent were satsifed and 31 percent were
Locoregional Failure of Post-Mastectomy Patients Who Had 1-3 Positive Axillary Lymph Nodes without Adjuvant Radiotherapy Presenter: C. Cheng Presenter's Affiliation: Sun Yat-Sen Cancer Center Type of Session: Scientific Background Post-mastectomy radiation is routinely given for patients with 4 or more positive lymph nodes to reduce locoregional failure. However, optimal adjuvant treatment for those with 1-3 positive lymph nodes is debated. This study was
Eighteen-Year Results in the Treatment of Early-Stage Breast Cancer With Breast Conservation Versus Mastectomy Presenter: Matthew PoggiPresenter's Affiliation: Radiation Oncology Branch, NCI, Bethesda, MDType of Session: ScientificBackground Several randomized clinical trials comparing conservative surgery followed by whole breast irradiation to mastectomy for patients with early stage breast cancer have reported long-term outcomes. These studies include
The 2006 Worldwide Overview of the Effects of Local Treatments for Early Breast Cancer On Long-term Outcome? "Meta-analysis of the Randomized Trials of Radiotherapy After Mastectomy With Axillary Clearance" Presenter: Paul McGale, PhDPresenter's Affiliation: Clinical Trial Service Unit, United KingdomType of Session: PlenaryBackground Randomized trials have shown that post-mastectomy radiation therapy ( PMRT ) confers both a local control and survival benefit in certain patient populations. It is generally accepted that patients with 4 or
The 2006 Worldwide Overview of the Effects of Local Treatments for Early Breast Cancer On Long-term Outcome? "Meta-analysis of the Randomized Trials of Radiotherapy After Mastectomy With Axillary Clearance" The 2006 Worldwide Overview of the Effects of Local Treatments for Early Breast Cancer On Long-term Outcome? "Meta-analysis of the Randomized Trials of Radiotherapy After Mastectomy With Axillary Clearance" It is well understood that radiation therapy after mastectomy ( PMRT ) improves survival and decreases recurrence rates in women
Chest Wall Radiation Alone for Breast Cancer Patients With 1-3 Positive Lymph Nodes Treated by Mastectomy Presenter: Shannon M. MacDonald, MDPresenter's Affiliation: Massachusetts General HospitalType of Session: ScientificBackground Numerous studies have demonstrated that the administration of adjuvant comprehensive postmastectomy radiation, which includes radiation to the chest wall and supraclavicular region, reduces locoregional recurrences
Ten-year Results of a Randomized Trial of Internal Mammary Chain Irradiation after Mastectomy Presenter: P. RomestaingPresenter's Affiliation: Centre De Radiotherapie Charcot, Ste Foy Les Lyon, FranceType of Session: PlenaryBackground Radiation delivery to nodal regions following mastectomy for breast cancer remains controversial. Among clinical discussion points remains the question of the need for delivery
Cardiac Toxicity is Not Increased 25 Years After Treatment of Early Stage Breast Carcinoma With Mastectomy or Breast Conservation Therapy From the National Cancer Institute Randomized Trial Abstract # 87 Presenting Author: Charles B. Simone, II, MD Presenting Author's Affiliation: Hospital of the University of Pennsylvania, Department of Radiation Oncology, Philadelphia, PA Background The current options for the treatment of early-stage breast cancer are modified radical mastectomy or breast-conserving surgery plus
The Mastectomy Poems: 2. The Gurney What's this long corridor above the street What are these glazed beige tiles Why in my horizontal state Am I so like an undemanding child After they wheel me in my bassinet Into the operating room Who made the muslin sheets so dry and white Over my humid body's doom How radiant the ceiling lights, of course They buzz appealingly for
The Mastectomy Poems: 1. The Bridge You never think it will happen to you, What happens every day to other women. Then as you sit paging a magazine, Its beauties lying idly in your lap, Waiting to be routinely waved good-bye Until next year, the mammogram technician Says, Sorry, we need to do this again, And you have already become a statistic, Citizen
The Mastectomy Poems 12. Epilogue: Nevertheless The bookbag on my back, I'm out the door. Winter turns to spring The way it does, and I buy dresses. A year later, it gets to where When they say How are you feeling, With that anxious look on their faces, And I start to tell them the latest About my love life or my kids' love lives, Or my vacation or my writer's block- It actually takes
Finding and Fitting a Breast Form: Tips for Breast Cancer Survivors Women with breast cancer face several cosmetic changes that may affect their body image and quality of life, including the loss of one or both breasts. In order to feel better about themselves and their bodies, some women may choose to be fitted with a breast prosthesis. Breast prostheses are breast forms that are put inside a bra to make your
Follow Up After Bilateral Mastectomy Question What is the current advice on post bilateral mastectomy follow up, short term and long term (mammograms, manual palpation, mri's etc.? Answer Gary Freedman, MD, Radiation Oncologist at Penn , responds: After a woman has undergone a bilateral mastectomy, the usual follow up is an examination by a heath professional twice a year and
Lumpectomy Versus Mastectomy Question I have been given the choice of lumpectomy and radiation vs. Mastectomy. Can you please give some advice to help me make my decision? Is one treatment better than the other? Answer Gary Freedman, MD, Radiation Oncologist at Penn , responds: Lumpectomy and radiation have been proven in large, well done clinical trials to result in equal