Hand Foot Syndrome

HFS is a skin reaction that appears on the palms of the hands and/or the soles of the feet as a result of certain chemotherapy agents. It may also be referred to as acral erythema, palmar plantar erythema (PPE), or Burgdorf reaction.


Hand-Foot Syndrome

This handout answers questions about and offers tips for managing hand-foot syndrome caused by chemotherapy.

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