Temozolomide (Temodar®), Oral Formulation
Temozolomide kills cancer cells through a process called alkylation. Alkylation damages the DNA of cells, which prevents them from dividing and causes them to die. Since cancer cells divide faster than healthy cells, cancer cells are more sensitive to this damage.
Temozolomide is similar to the drug dacarbazine (DTIC). Patients who have had allergic reactions to dacarbazine should not take temozolomide.