Self-Collection Testing for HPV

Author: Allyson Van Horn, MPH
Last Reviewed: January 22, 2026

Most cases of cervical cancer are caused by HPV (Human Papillomavirus). The American College of Obstetricians and Gynecologists (ACOG) recommends that anyone with a cervix between the ages of 30 and 65 should be tested for HPV. This type of testing can be done by a provider in the office (preferred way) or by self-collection. Self-collection testing is now an option if you are at average risk of cervical cancer and prefer not to have a pelvic exam done by your healthcare provider.

What is self-collection testing?

Self-collection testing is a way to test for HPV that you can do yourself without needing a speculum. The self-collection test must be ordered by your healthcare provider. The test may be done at home or in a private room at your healthcare clinic, depending on your provider’s orders and your preferences. The Food and Drug Administration (FDA) has approved a few kits for self-collection. Talk to your provider about your options.

How are self-collection tests done?

Self-collection test kits come with instructions on how to use them. You will use the swab in the kit to collect a sample from your vagina. Then, depending on whether you are doing the self-collection test at home or in a clinic, you or your provider will send your sample to a lab where it will be tested.

How often are self-collection tests done?

It is recommended that self-collection be used for people who have an average risk of HPV rather than a high risk. If the self-collection test is negative, then it should be done every 3 years. If your self-collection test is positive or abnormal, you will need to have more testing. Your provider will tell you what steps to take.

Self-collection should not be used if you:

  • Had an abnormal cervical screening in the past.
  • Have HIV.
  • Have a weakened immune system.
  • Were exposed to DES before birth.

Talk with your provider about when and how you should be screened for cervical cancer.